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what is the difference between scleroderma and systemic sclerosis ?

Asked By: luobo1689 | Last Updated: 2022-05-26

what is the difference between scleroderma and systemic sclerosis?

What's the difference between scleroderma and systemic sclerosis? Scleroderma is seen only on the skin. However, when the fibrosis involves your other internal organs, this is considered systemic sclerosis.

Then,Is sclerosis the same as scleroderma?

Scleroderma (sklair-oh-DUR-muh), also known as systemic sclerosis, is a group of rare diseases that involve the hardening and tightening of the skin. It may also cause problems in the blood vessels, internal organs and digestive tract.

Long,What is the difference between scleroderma and systemic scleroderma?

Localized scleroderma: often affects only the skin and not major organs. Systemic scleroderma: affects the skin and may affect the tissues under it, including blood vessels and major organs, such as the gastrointestinal tract, heart, lungs or kidneys.

In this way,Is SSc the same as scleroderma?

When scleroderma only affects the skin, it is considered "localized." However, if it affects the skin and internal organs, it is viewed as "systemic" and called systemic sclerosis (SSc). SSc affects approximately 100,000 people, or about one third of individuals with scleroderma in the United States.

Furthermore,How long can you live with systemic sclerosis?

Patients with limited cutaneous systemic sclerosis have a 10-year survival estimate of approximately 90%. However, development of interstitial lung disease (ILD) or pulmonary artery hypertension (PAH) dramatically increases the risk of death.

Related Question Answers Found

Which organ is most frequently affected in systemic sclerosis?

PAH and ILD are progressive conditions and can eventually become life-threatening. Taken together, they account for about half of all deaths related to systemic scleroderma. The most commonly involved part of the gastrointestinal tract in systemic scleroderma is the esophagus.

What test confirms scleroderma?

Electrocardiogram (EKG or ECG) to see if there are changes in the heart muscle tissue due to scleroderma. An EKG/ECG records the electrical activity of the heart, shows abnormal rhythms and detects any damage.

How serious is systemic sclerosis?

Sometimes systemic sclerosis worsens rapidly and becomes fatal (mainly with diffuse systemic sclerosis). At other times, it affects only the skin for decades before affecting internal organs, although some damage to internal organs (such as the esophagus) is almost inevitable. The course is unpredictable.

What is the survival rate for scleroderma?

Systemic sclerosis (scleroderma) runs a variable course. A review of 11 studies, totalling over 2000 patients, revealed 5-year cumulative survival rates ranging from 34 to 73 per cent, with a mean of 68 per cent [I]. Organ failure is generally regarded as the major cause of death in this disease.

What virus causes scleroderma?

One theory suggests that scleroderma is caused by a virus or other infection. For example, a common virus called CMV (cytomegalovirus) is known to infect cells (endothelial cells) that line our blood vessels, which we know are diseased in scleroderma (3).

What can mimic scleroderma?

However, similar features of hard and thick skin can be seen in other conditions which are often referred to as “scleroderma mimics”. These mimics include eosinophilic fasciitis, nephrogenic systemic fibrosis, scleromyxedema, and scleredema among others.

Is ANA positive in scleroderma?

Approximately 95% of people with systemic scleroderma have a positive antinuclear antibody (ANA) test, but so do people with other autoimmune diseases (97% of people with lupus, as an example). People with localized scleroderma usually have negative ANA.

How do you rule out scleroderma?

To diagnose scleroderma, a doctor usually begins by asking you about your symptoms, health, and medical history. The doctor will also examine your skin for signs of hardening and thickening. If you have hard, thickened skin, a dermatologist may perform a skin biopsy to help diagnose you.