what is multiple system atrophy ?
what is multiple system atrophy？
Multiple system atrophy (MSA) is a rare, degenerative neurological disorder affecting your body's involuntary (autonomic) functions, including blood pressure, breathing, bladder function and motor control.2020年5月21日
Considering this,What are the first signs of MSA?
What are the symptoms of MSA? Most often, the first clinical symptom a patient will note will be lightheadedness, dizziness, and episodes of passing out, but the first symptoms in some patients may include difficulty initiating movement, body stiffness, urinary incontinence, and increased falls.
Furthermore,Is multiple system atrophy fatal?
Multiple system atrophy is a progressive, fatal disorder that makes muscles stiff (rigid) and causes problems with movement, loss of coordination, and malfunction of internal body processes (such as blood pressure and bladder control).
Subsequently, question is,What is the treatment for MSA?
There is no specific treatment for MSA. Treatment is aimed at controlling the symptoms of the disease. Drugs that are used to treat people with Parkinson's disease, most notably levodopa (given in tablets of Sinemet), may also be prescribed for individuals with MSA.
Keeping this in consideration,Is MSA a terminal illness?
Because MSA is at this time a terminal disease with mean patient survival of 6 to 10 years after the onset of symptoms, patients and families should begin to make decisions regarding advanced directives, finances, hospice care, and the possibility of brain donation, if so desired.
People typically live about seven to 10 years after multiple system atrophy symptoms first appear. However, the survival rate with MSA varies widely. Occasionally, people can live for 15 years or longer with the disease. Death is often due to respiratory problems.
A major clinical dilemma is whether a patient with parkinsonism has Parkinson disease (PD) or MSA, as the prognosis of MSA is much worse. Autonomic involvement is common in PD but is more variable in severity than MSA. Mild OH is relatively common in PD and occasionally severe OH can occur.
Six months of resistance training with instability alleviate the MSA-related effects and improve the quality of life in a patient with MSA. High complexity exercise intervention (i.e., resistance training with instability) may be very beneficial to individuals with impaired motor control and function as MSA patients.
Most cases of multiple system atrophy are sporadic, which means they occur in people with no history of the disorder in their family. Rarely, the condition has been reported to run in families; however, it usually does not have a clear pattern of inheritance.
There's currently no cure for MSA and no way of slowing its progression. People with the condition typically live for 6 to 9 years after their symptoms start and may get worse quickly during this time. Some people may live for more than 10 years after being diagnosed.
The cause of multiple system atrophy (MSA) remains unknown, and no current therapy can reverse or halt progression of the disease. The extrapyramidal and cerebellar aspects of the disease are debilitating and difficult to treat.
There are three levels of certainty: Possible, probable and definate. The diagnosis of possible MSA and probable MSA basically involves having more of these features.
If your doctor suspects multiple system atrophy, he or she will obtain a medical history, perform a physical examination and possibly order blood tests. Brain imaging scans, such as an MRI , can show signs that may suggest MSA and also help determine if there are other causes that may be contributing to your symptoms.