what are white matter hyperintensities ?
what are white matter hyperintensities？
Abstract. White matter hyperintensities (WMHs) are brain white matter lesions that are hyperintense on fluid attenuated inversion recovery (FLAIR) magnetic resonance imaging (MRI) scans. Larger WMH volumes have been associated with Alzheimer's disease (AD) and with cognitive decline.2020年2月1日
Keeping this in consideration,What do white matter hyperintensities indicate?
Conclusion White matter hyperintensities predict an increased risk of stroke, dementia, and death. Therefore white matter hyperintensities indicate an increased risk of cerebrovascular events when identified as part of diagnostic investigations, and support their use as an intermediate marker in a research setting.
Additionally,What causes white matter hyperintensities on MRI?
Incident stroke Indeed, age and hypertension are the main predictors of white matter hyperintensities,69 70 and other vascular risk factors such as smoking, diabetes, and history of vascular disease were also shown to be associated with lesions in white matter.
Thereof,Is it normal to have white matter hyperintensities?
White matter hyperintensities are common in MRIs of asymptomatic individuals, and their prevalence increases with age from approximately 10% to 20% in those approximately 60 years old to close to 100% in those older than 90 years.
One may also ask,Can white matter hyperintensities go away?
Sometimes a white spot can go away if treated—for example, if it is an infection or brain tumor. They may also temporarily get smaller and possibly worsen again later. This is often the case with inflammatory conditions such as lupus or MS that flare up and then improve.
Fisher's exact test showed that the prevalence of WMHs was higher in the 41 to 50 age-range group than in the less-than-40 group (P < 0.0001), and higher in the 51 to 60 age-range group than in the 41 to 50 age-range group (P < 0.0001), and higher in the 61 to 70 age-range group than in the 51 to 60 age-range group (P ...
White matter disease is commonly detected on brain MRI of aging individuals as white matter hyperintensities (WMH), or 'leukoaraiosis.” Over the years it has become increasingly clear that the presence and extent of WMH is a radiographic marker of small cerebral vessel disease and an important predictor of the life- ...
White matter lesions are among the most common incidental findings—which means the lesions have no clinical significance—on brain scans of people of any age. They may also reflect a mixture of inflammation, swelling, and damage to the myelin.
There isn't a specific treatment. The goal is to treat the cause of the damage and stop the disease from getting worse. Your doctor may prescribe medicines to lower your blood pressure or cholesterol.
White matter disease may develop with conditions associated with aging, such as stroke, but it can also affect young people due to conditions such as cerebral adrenoleukodystrophy and multiple sclerosis (MS). Read on to learn more about white matter disease and its symptoms, causes, and prognosis.
The life expectancy after a diagnosis of white matter disease depends on the speed it progresses and the severity of any other conditions it may cause, like stroke and dementia. White matter disease is believed to be a factor in both strokes and dementia. However, more research must be done for further confirmation.
Although white-matter lesions are viewed as a normal part of aging, and are found in people with no dementia or other neurocognitive disorders, they are linked with other health problems.
Patients with extensive white matter hyperintensities are likely to have tension-type headaches or to have headaches develop during middle age, according to results published in Cephalagia. Currently, there are no established treatments or strategies for managing white matter hyperintensities.